中医急救法十二井穴放血与甘露醇的比较研究


Blood-lettingpuncturesattwelveJing-Wellpointsofthehandcantreatcerebralischemiainasimilarmannertomannitol

十二井穴刺血疗法可与甘露醇相似作用方式治疗大脑缺血状态

Abstract

AratmodelofmiddlecerebralarterypermanentocclusionwasestablishedusingthemodifiedLongamethod.Successfullyestablishedmodelanimalsweretreatedbyblood-lettingpunctureattwelveJing-Wellpointsofthehand,and/orbyinjectingmannitolintothecaudalveintwicedaily.Braintissuewascollectedat24,48and72hoursaftermodeling,andbloodwascollectedthroughtheretinalveinbeforeEvansbluewasinjected,approximately1hourpriortoharvestingofbraintissue.ResultsshowedthatEvansblueleakageintobraintissueandserumnitricoxidesynthaseactivityweresignificantlyincreasedinmodelrats.Treatmentwithblood-lettingpuncturesattwelveJing-Wellpointsofthehandand/orinjectionofmannitolintothecaudalveinreducedtheamountofEvansblueleakageintothebraintissueandserumnitricoxidesynthaseactivitytovaryingdegrees.Therewasnosignificantdifferencebetweensingletreatmentand







































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